While weight regain is common after stopping any weight-loss medication, its not inevitable
Weight reduction in kilograms was not taken into account, because the initial body weight of patients with PCOS varied in several of the studies included
It lists nausea, vomiting, and constipation as frequent during titration, with pancreatitis, gallbladder disease, and retinopathy as rarer serious concerns
Among GLP-1 medications specifically, semaglutide has one of the longest half-lives: Exenatide (Byetta): approximately 2.4 hours, requires twice-daily injections Liraglutide (Saxenda, Victoza): approximately 13 hours, requires once-daily injections Dulaglutide (Trulicity): approximately 5 days, requires once-weekly injections Semaglutide (Ozempic, Wegovy): approximately 7 days, requires once-weekly injections Tirzepatide (Mounjaro, Zepbound): approximately 5 days, requires once-weekly injections Semaglutides seven-day half-life ties it with dulaglutide for the longest among currently approved GLP-1 medications
